GarudaBW

15/605-606 mayuresh c.h.s., majaswadi mhada colony, off mahakali caves road, andheri (east), mumbai-400 093.

tel.: 022.2820.1198 28215596

fax.: 022.2820.1201

email.: gcsales@garudachem.com

 

Page 1/6

 

MATERIAL SAFETY DATA SHEET

 

 

SECTION 1: Identification of the substance/mixture and of the company/ undertaking

1.1 Product identifier

Product name:

Indole

CAS-No.

120-72-9

EC-No.

204-420-7

1.2 Relevant identified uses of the substance or mixture and uses advised against

Identified uses

Laboratory chemicals, Manufacture of substances

1.3 Details of the supplier of the safety data sheet

Safety Data Services

15/605-606 mayuresh c.h.s., majaswadi mhada colony, off mahakali caves road, andheri (east), mumbai-400 093.

1.4 Emergency telephone number

022.2820.1198 (1100 hrs GMT to 1900 hrs GMT)

 

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

Not a dangerous substance according to GHS.

Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP

Acute toxicity, Oral (Category 4)

Acute toxicity, Dermal (Category 3)

Skin irritation (Category 2)

Serious eye damage (Category 1)

Specific target organ toxicity - single exposure (Category 3)

Acute aquatic toxicity (Category 1)

Classification according to EU Directives 67/548/EEC or 1999/45/EC

Harmful in contact with skin and if swallowed. Irritating to respiratory system and skin. Risk of serious

damage to eyes. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic

environment.

 

2.2 Label elements

This substance is not classified as dangerous according to Directive 67/548/EEC.

Labelling according Regulation (EC) No 1272/2008 [CLP]

Pictogram

Signal word Danger

Hazard statement(s)

H302 Harmful if swallowed.

H311 Toxic in contact with skin.

H315 Causes skin irritation.

H318 Causes serious eye damage.

H335 May cause respiratory irritation.

H400 Very toxic to aquatic life.

Precautionary statement(s)

P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.

P273 Avoid release to the environment.

P280 Wear protective gloves/ eye protection/ face protection.

P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove

contact lenses, if present and easy to do. Continue rinsing.

P312 Call a POISON CENTER or doctor/ physician if you feel unwell.

Supplemental Hazard none

Statements

According to European Directive 67/548/EEC as amended.

Hazard symbol(s)

R-phrase(s)

R21/22 Harmful in contact with skin and if swallowed.

R37/38 Irritating to respiratory system and skin.

R41 Risk of serious damage to eyes.

R50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in

the aquatic environment.

S-phrase(s)

S26 In case of contact with eyes, rinse immediately with plenty of water and

seek medical advice.

S36/37/39 Wear suitable protective clothing, gloves and eye/face protection.

S60 This material and its container must be disposed of as hazardous waste.

S61 Avoid release to the environment. Refer to special instructions/ Safety

data sheets.

2.3 Other hazards none

Stench.

 

 

 


 

GarudaBW

15/605-606 mayuresh c.h.s., majaswadi mhada colony, off mahakali caves road, andheri (east), mumbai-400 093.

tel.: 022.2820.1198 28215596

fax.: 022.2820.1201

email.: gcsales@garudachem.com

 

Page 2/6

 

MATERIAL SAFETY DATA SHEET

 

Indole

SECTION 3: Composition/information on ingredients

3.1 Substances

 

Formula

C8H7N

Molecular Weight

117,15 g/mol

Component

Concentration

Indole

 

CAS-No. 120-72-9

 

EC-No. 227-526-5

 

 

SECTION 4: First aid measures

4.1 Description of first aid measures

General advice Consult a physician. Show this safety data sheet to the doctor in

attendance

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms and effects, both acute and delayed

Nausea, Headache, Vomiting, To the best of our knowledge, the chemical, physical, and toxicological

properties have not been thoroughly investigated.

4.3 Indication of any immediate medical attention and special treatment needed

no data available

 

 
SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Special hazards arising from the substance or mixture

Carbon oxides. nitrogen oxides (NOx)

5.3 Advice for firefighters

Wear self contained breathing apparatus for fire fighting if necessary.

5.4 Further information

no data available

 

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Wear respiratory protection. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate

ventilation. Evacuate personnel to safe areas. Avoid breathing dust.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the

environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed

containers for disposal.

6.4 Reference to other sections

For disposal see section 13.

 


 

GarudaBW

15/605-606 mayuresh c.h.s., majaswadi mhada colony, off mahakali caves road, andheri (east), mumbai-400 093.

tel.: 022.2820.1198 28215596

fax.: 022.2820.1201

email.: gcsales@garudachem.com

 

Page 3/6

 

MATERIAL SAFETY DATA SHEET

 

Indole

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols.

Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire

protection.

7.2 Conditions for safe storage

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Air and light sensitive.

7.3 Specific end uses

no data available

 

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Components with workplace control parameters

8.2 Exposure controls

Appropriate engineering controls

Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling

the product.

Personal protective equipment

Eye/face protection

Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Body Protection

Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

 

 

 


 

GarudaBW

15/605-606 mayuresh c.h.s., majaswadi mhada colony, off mahakali caves road, andheri (east), mumbai-400 093.

tel.: 022.2820.1198 28215596

fax.: 022.2820.1201

email.: gcsales@garudachem.com

 

Page 4/6

 

MATERIAL SAFETY DATA SHEET

 

Indole

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties

Appearance

Form: flakes

 

Colour: light brown

Odour

no data available

Odour Threshold

no data available

pH

no data available

Melting point

 

Melting point/range: 51 - 54 C - lit.

Initial boiling point and

boiling range

253 - 254 C - lit.

Flash point

121 C - closed cup

Evaporation rate

no data available

Flammability (solid, gas)

no data available

Upper explosion limit no data available

Vapour pressure no data available

Vapour density no data available

Relative density 0,864 g/cm3 at 25 C

Water solubility no data available

Partition coefficient: no data available

noctanol/

water

Autoignition no data available

temperature

Decomposition no data available

temperature

Viscosity no data available

Explosive properties no data available

Oxidizing properties no data available

9.2 Other safety information

no data available

 

 

SECTION 10: Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

no data available

10.3 Possibility of hazardous reactions

no data available

10.4 Conditions to avoid

Air Light.

10.5 Incompatible materials

Strong oxidizing agents, Iron and iron salts.

10.6 Hazardous decomposition products

Other decomposition products - no data available


 

GarudaBW

15/605-606 mayuresh c.h.s., majaswadi mhada colony, off mahakali caves road, andheri (east), mumbai-400 093.

tel.: 022.2820.1198 28215596

fax.: 022.2820.1201

email.: gcsales@garudachem.com

 

Page 5/6

 

MATERIAL SAFETY DATA SHEET

 

Indole

SECTION 11: Toxicological information

 

11.1 Information on toxicological effects

 

Acute toxicity

 

LD50 Oral - rat - 1.000 mg/kg

 

LD50 Dermal - rabbit - 790 mg/kg

 

Skin corrosion/irritation

 

Serious eye damage/eye irritation

 

Eyes - rabbit - Severe eye irritation - 24 h

 

Respiratory or skin sensitization

 

no data available

 

Germ cell mutagenicity

 

no data available

 

Carcinogenicity

 

Carcinogenicity - mouse - Subcutaneous

 

Tumorigenic:Equivocal tumorigenic agent by RTECS criteria. Lungs, Thorax, or Respiration:Tumors.

 

Leukaemia

 

Carcinogenicity - mouse - Subcutaneous

 

Tumorigenic:Equivocal tumorigenic agent by RTECS criteria. Tumorigenic:Tumor types after systemic

 

administration not seen spontaneously.

 

IARC:

No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.

 

Reproductive toxicity

 

no data available

 

Specific target organ toxicity - single exposure

 

Inhalation - May cause respiratory irritation.

 

Specific target organ toxicity - repeated exposure

 

no data available

 

Aspiration hazard

 

no data available

 

Potential health effects

 

Inhalation

May be harmful if inhaled. Causes respiratory tract irritation.

Ingestion

Harmful if swallowed.

Skin

Toxic if absorbed through skin. Causes skin irritation.

Eyes

Causes eye burns.

Signs and Symptoms of Exposure

 

Nausea, Headache, Vomiting, To the best of our knowledge, the chemical, physical, and toxicological

 

properties have not been thoroughly investigated

 

RTECS: NL2450000

 

 

SECTION 12: Ecological information

12.1 Toxicity

Toxicity to daphnia and LC50 - Daphnia magna (Water flea) - 1 mg/l - 48 h

other aquatic

invertebrates

Toxicity to algae Growth inhibition EC100 - Scenedesmus acuminatus - > 10 mg/l - 96 h

12.2 Persistence and degradability

Not available.

12.3 Bioaccumulative potential

Not available.

12.4 Mobility in soil

Not available.

12.5 Results of PBT and vPvB assessment

Not available.

12.6 Other adverse effects

Very toxic to aquatic life.


 

GarudaBW

15/605-606 mayuresh c.h.s., majaswadi mhada colony, off mahakali caves road, andheri (east), mumbai-400 093.

tel.: 022.2820.1198 28215596

fax.: 022.2820.1201

email.: gcsales@garudachem.com

 

Page 6/6

 

MATERIAL SAFETY DATA SHEET

 

Indole

SECTION 13: Disposal considerations

13.1 Waste treatment methods

Product

Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed

professional waste disposal service to dispose of this material. Dissolve or mix the material with a

combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.

Contaminated packaging

Dispose of as unused product.

 

SECTION 14: Transport information

14.1 UN number

ADR/RID: - 2811 IMDG: - 2811 IATA: - 2811

14.2 UN proper shipping name

ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. (Indole)

IMDG: TOXIC SOLID, ORGANIC, N.O.S. (Indole)

IATA: Toxic solid, organic, n.o.s. (Indole)

14.3 Transport hazard class(es)

ADR/RID: - 6.1 IMDG: - 6.1 IATA: - 6.1

14.4 Packaging group

ADR/RID: - III IMDG: - III IATA: - III

14.5 Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA: no

14.6 Special precautions for user

no data available

 

SECTION 15: Regulatory information

15. This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

no data available

15.2 Chemical Safety Assessment

no data available

 

SECTION 16: Other information

Notice to reader

The statements contained herein are based upon technical data that Garuda Chemicals believes to be reliable, are offered for information purposes only and as a guide to the appropriate precautionary and emergency handling of the material by a properly trained person having the necessary technical skills. Users should consider these data only as a supplement to other information gathered by them and must make independent determinations of suitability and completeness of information from all sources to assure proper use, storage and disposal of these materials and the safety and health of employees and customers and the protection of the environment.

 

BACK